Antibiotic resistance in bacteria are an escalating problem. Little is known about the potential of microorganisms in sites affected by acid mine drainage (AMD) to be sources of new antibiotics. Sediments from AMD sites in Letcher County, Kentucky, were collected and microorganisms isolated. These samples were screened for their capacity to produce antimicrobial compounds active against known bacteria E. coli and S. aureus. The results showed no antimicrobial activity. This could be due to sample death, incorrect pH of media, or antibiotic resistance already present in the AMD site.

Semester/Year of Award

Fall 11-30-2020


Dr. Bill Staddon

Mentor Department Affiliation

Biological Sciences

Access Options

Open Access Thesis

Document Type

Bachelor Thesis

Degree Name

Honors Scholars

Degree Level



Biological Sciences